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Green Fluorescent Protein Indicating Redox Potential

Changes in the redox equilibrium of cells influence a host of cell functions. Redox-sensitive green fluorescent proteins (GFP) allow real time visualization of the oxidation state of a cell.

Published: 6/3/2009 | Updated: 5/29/2009 | Inventor(s): James Remington

Keywords(s):

Category(s): Research tools

Mutant Fluorescent Proteins

Functional engineered fluorescent proteins with varied fluorescence characteristics that can be easily distinguished from currently existing green and blue fluorescent proteins. Such engineered fluorescent proteins enable the simultaneous measurement of two or more processes within cells and can be used as fluorescence energy donors or acceptors...

Published: 6/3/2009 | Updated: 5/27/2009 | Inventor(s): Rebekka Wachter, Atsushi Miyawaki, Juan Llopis, Roger Heim, James Remington, Roger Tsien, Andrew Cubbit, Matts Ormo

Keywords(s): Research Tools

Category(s): Research tools

Use of Pentamidine in Myotonic Dystrophy Models

Myotonic Dystrophy is characterized by 200–2000 CUG repeats in the 3’UTR of the DMPK gene—unaffected individuals have 5–35 CUG repeats. The CUG repeats form a stem-loop and it’s been suggested that this is a gain-of-function mutation wherein the stem loop binds proteins in the cell so that the proteins are unavailable to perform their normal cellular...

Published: 7/27/2009 | Updated: 5/22/2009 | Inventor(s): Andy Berglund, Bryan Warf, Leslie Vanos, Catherine Matthys

Keywords(s): Chemical, Therapeutics

Category(s): Research tools

Culture Collection of Microorganisms from Extreme Environments

The Culture Collection of Microorganisms from Extreme Environments (CCMEE) was created in 1999 by the consolidation of the collections of Dr. E. Imre Friedmann of Florida State University and Dr. Richard Castenholz of the University of Oregon. The newly-formed CCMEE contains cultures from all over the world, including Antarctica, Israel, Asia, Africa,...

Published: 6/3/2009 | Updated: 5/22/2009 | Inventor(s): Richard Castenholz, Christopher Wingard

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Category(s): Research tools

Monoclonal Antibodies

The University of Oregon's Monoclonal Antibody Facility, in close collaboration with university researchers, developed novel monoclonal antibodies against a variety of proteins and peptides that are used in studies of molecular structure, subcellular activities, and cellular differentiation. Many of these monoclonal antibodies are now available through...

Published: 6/4/2009 | Updated: 2/19/2009 | Inventor(s):

Keywords(s): Antibodies, Biological Materials, Research Tools

Category(s): Research tools